Pain Science Education and Central Sensitization

Pain Science Education and Central Sensitization

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“But nothing showed up on the MRI…”
If you’ve worked with people experiencing chronic pelvic pain, you’ve likely heard this line (or screamed it into the void yourself). Pelvic pain is complex. It’s layered. And when traditional diagnostic tools come up short, patients are left confused, discouraged, and often dismissed.

This is where pain science education becomes not just helpful—it becomes essential. Especially when we’re talking about central sensitization, a sneaky, brain-driven process that keeps the pain party going long after the tissue has healed.

Let’s dig into what this means for our pelvic pain population—and why it’s time every clinician added “pain science educator” to their superpower list.

What Is Central Sensitization?
Imagine your nervous system is like a home security system. Normally, it detects real threats—say, a break-in or fire. But in central sensitization, the system is so sensitive that it goes off when a leaf blows past the window. The brain and spinal cord amplify pain signals, misinterpreting non-threatening input (like gentle touch, muscle movement, or a full bladder) as dangerous.

In the pelvic floor world, this might look like:

  • Burning with urination despite no infection
  • Pain with penetration, even with no visible tissue damage
  • A “tight” pelvic floor that resists every stretch and cue
  • General pain or pressure that moves, shifts, or seems unprovoked

Central sensitization isn’t “in someone’s head.” It’s in their nervous system—and it’s very, very real.

Why Pain Education Matters
Pain science education helps patients reframe their experience. When someone understands that pain is a protective mechanism (not a damage report), the fear cycle begins to break.

This is huge in chronic pelvic pain. Patients often carry shame, confusion, and even trauma around their symptoms. By educating them about central sensitization, we:

  • Reduce fear and catastrophizing
  • Improve trust in the body
  • Increase compliance with movement and manual therapy
  • Promote neuroplastic healing (yes, the brain can change!)

Think of it this way: You wouldn’t start strength training a rotator cuff tear without explaining what’s happening first. The same rules apply here—except our “tear” is happening at the nervous system level.

How to Integrate Pain Science into Pelvic Floor Treatment
You don’t need to be a neuroscientist or TED Talker to do this well. Here’s how we incorporate pain education into every evaluation and treatment session:

  1. Use Metaphors that Stick

The alarm system analogy is a go-to. Others include:

  • “Your brain is trying to protect you, but it’s become a little overprotective.”
  • “Your nervous system is on high alert like a smoke detector that’s too close to the toaster.”
  1. Normalize Their Experience

Validate their symptoms without reinforcing fear. “Your body is reacting in a protective way. We can help it learn to feel safe again.”

  1. Introduce the Concept of Graded Exposure

Reassure them that movement, intimacy, and bladder function can return—gradually, safely, and with support. We’re not rushing into the fire; we’re slowly turning down the alarm.

  1. Keep Repeating the Message

It takes time for the nervous system—and the brain—to rewire. Repeat, reframe, and reinforce education at every visit.

The Future of Pelvic Health Is Brain-Based
Pelvic pain isn’t just a musculoskeletal issue—it’s a nervous system experience. And the more we understand central sensitization, the better we can support our patients.

Pain education isn’t fluff. It’s foundational. It’s empowering. And it may just be the first real explanation your patient has ever received.

So, let’s keep spreading the word, turning down alarms, and helping patients feel safe in their bodies again.

Because healing starts with understanding—and we’ve got a lot of explaining to do (in the best way possible).

Want to dive deeper into the why behind pain?
Learn how to distinguish between peripheral pain generators and central sensitization, understand how these mechanisms show up in the body, and gain practical strategies to address them in both pelvic pain and orthopedic patients.

Join us for our remote pain science course, Pain Science for the Chronic Pelvic Pain Population on June 21-22, where complex concepts meet clear, clinical application, even including verbatim script examples with real-life patients.

AUTHOR BIO
Tara Sullivan, PT, DPT, PRPC, WCS, IF

Sullivan 2021Dr. Tara Sullivan, PT, PRPC, WCS, IF (she/her) started in the healthcare field as a massage therapist practicing for over ten years, including three years of teaching massage and anatomy & physiology. During that time, she attended college at Oregon State University, earning her Bachelor of Science degree in Exercise and Sport Science, and she continued to earn her Master of Science in Human Movement and Doctorate in Physical Therapy from A.T. Still University. Dr. Tara has specialized in Pelvic Floor Dysfunction (PFD), treating bowel, bladder, sexual dysfunctions, and pelvic pain exclusively since 2012. She has earned her Pelvic Rehabilitation Practitioner Certification (PRPC), deeming her an expert in the field of pelvic rehabilitation, treating men, women, and children. Dr. Sullivan is also a board-certified clinical specialist in women’s health (WCS) through the APTA and a Fellow of the International Society for the Study of Women's Sexual Health (IF).

Dr. Tara established the pelvic health program at HonorHealth in Scottsdale and expanded the practice to 12 locations across the valley. She continues treating patients with her hands-on individualized approach, taking the time to listen and educate them, empowering them to return to a healthy and improved quality of life. Dr. Tara has developed and taught several pelvic health courses and lectures at local universities in Arizona, including Northern Arizona University, Franklin Pierce University, and Midwestern University. In 2019, she joined the faculty team at Herman and Wallace, teaching continuing education courses for rehab therapists and other health care providers interested in the pelvic health specialty, including a course she authored-Sexual Medicine in Pelvic Rehab, and co-author of Pain Science for the Chronic Pelvic Pain Population. Dr. Tara is very passionate about creating awareness of Pelvic Floor Dysfunction and launched her website pelvicfloorspecialist.com to continue educating the public and other healthcare professionals.

In March 2024, Dr. Tara left HonorHealth and founded her company, Mind to Body Healing (M2B), to continue spreading awareness on pelvic health, mentor other healthcare providers, and incorporate sexual counseling into her pelvic floor physical therapy practice. She has partnered with Co-Owner, Dr. Kylee Austin, PT.

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Two Questions: A Pair of Short Interviews From Two Pairs of Instructors

Two Questions: A Pair of Short Interviews From Two Pairs of Instructors

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Today The Pelvic Rehab Report is featuring two short interviews with instructor teams Alyson Lowrey & Tara Sulivan who teach Pain Science for the Chronic Pelvic Pain Population, and Sandra Gallagher & Caitlin Smigelski who teach Transgender Patients: Pelvic Health and Orthopedic Considerations.

 

The Pain Science for the Chronic Pelvic Pain Population instructors Alyson N Lowrey, PT, DPT, OCS &Tara Sullivan, PT, DPT, PRPC, WCS, IF answered the following two questions:

What Is Pain?
All pain occurs in the brain. Whether it is from acute tissue injury, nerve injury, or chronic pain, all pain has to be interpreted by the brain. How do you explain to a patient that their pain may not be from tissue damage, but from their brain interpreting something as painful that shouldn’t? While their pain may be in their brain, it is NOT in their head!

Pelvic pain is complicated because of a phenomenon called pelvic organ cross-talk. Your brain has a really hard time determining which pelvic organ or muscle is having pain or sensations, so signals can get crossed. Patients can present with uterine pain that can cause bowel or bladder pain and vice versa. We commonly see this with endometriosis and interstitial cystitis. Another example is the prostate and bladder. Prostatitis may present as an overactive bladder. This makes our jobs more difficult because we have to be able to determine the true source of a patient’s pain and understand that their pain may not be coming from an obvious source.

What is pain neuroscience education (PNE) and how can it be used?
Pain neuroscience education (PNE) is the explanation of the neurophysiological changes in the central nervous system to patients that have chronic pain. It is explaining pain, sensitization, and all the factors that can be contributing to their pain and abnormal sensations.

PNE typically decreases the threat value of pain, diminishes catastrophic thinking about pain, and facilitates a more active coping strategy. In the Pain Science for the Chronic Pelvic Pain Population, you will leave with the tools to combine pain science education with current interventions for a more effective treatment.

 

The Transgender Patients: Pelvic Health and Orthopedic Consideration instructors Sandra Gallagher, PT, DPT, WCS & Caitlin Smigelski, PT, DPT answered the following two questions:

What made you want to create this course?
We created this course on rehabilitation in gender-affirming care in 2018 because, at that time, nothing like it existed. We had learned so much from working with patients preparing for surgery and knew we need more information. Through attending conferences, we had opportunities to talk with experts in the field including surgeons, endocrinologists, primary care physicians, and social workers. Combined with researching additional topics, we made the course we wish we could have taken: a course that bridges physical rehabilitation considerations with medical and surgical information on transgender care.

Today, many brief courses and videos about gender-affirming care exist. You can now find courses and videos that address trauma-informed care, language aspects of gender-affirming care, and physicians and surgeons speaking on their procedures. We think this is great and encourage people to continue to seek out these learning opportunities! Our goal is to expand on the perspective of the rehab professional by offering a course that has both depth and breadth.

Our course has evolved to a hybrid format with pre-recorded self-paced lectures and live webinar content. We know that some participants are well versed in LGBTQ topics and are trained in providing trauma-informed care. For other participants, our course may be the first time they are exploring topics like sex, gender, sexuality, trauma-informed care, and gender-affirming language. The content in the pre-recorded lectures allows participants to work at their own pace, whether it is review or brand new information and allows everyone to have a similar foundation when we meet for the live portion.

What is your message to practitioners about gender-affirming care?
Our message to participants who are just starting their journey on gender-affirming care is to remember that gender is not genitals and that undergoing gender-affirming procedures is not strictly about sexual activity options. Sometimes people get so focused on the genital surgery or changes, that they forget the person. Every patient's path will be a bit different and there is more to gender-affirming care than peri-operative rehab.

Keep learning! Engage with professional organizations like WPATH, watch videos featuring gender diverse individuals, practice language with coworkers, and attend grand rounds. Many university hospitals now have virtual rounds that are available live or as recordings. There is so much information available if you search for it!

 


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Pain Science for the Chronic Pelvic Pain Population

Course Date: October 8-9, 2022
Price:$400
Experience Level: Beginner
Contact Hours: 12

Description: This course is designed to expand the participant's knowledge, experience, and treatment in understanding and applying pain science to the chronic pelvic pain population including endometriosis, interstitial cystitis, irritable bowel syndrome, vaginismus, vestibulodynia, primary dysmenorrhea, and prostatitis. This course provides a thorough introduction to pain science concepts including classifications of pain mechanisms, peripheral pain generators, peripheral sensitization, and central sensitization in listed chronic pelvic pain conditions; as well as treatment strategies including therapeutic pain neuroscience education, therapeutic alliance, and the current rehab interventions' influence on central sensitization.

Lecture topics include the history of pain, pain physiology, central and peripheral sensitization, sensitization in chronic pelvic pain conditions, therapeutic alliance, pain science and trauma-informed care, therapeutic pain neuroscience education, the influence of rehab interventions on the CNS, and specific case examples for sensitization in CPP.

 

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Transgender Patients: Pelvic Health and Orthopedic Considerations

Course Date: October 8,2022
Price: $500
Experience Level: Beginner
Contact Hours: 17

Description:  This course is appropriate for any physical rehabilitation professional, regardless of their specialty area, who has an interest in better serving people who are gender diverse. There is specific content aimed at teaching pelvic health therapists how to expand their skills for working with people of all gender identities. There will be particular education regarding gender-affirming genital surgeries as well as discussion of other gender-affirming surgeries and medical interventions that people transitioning might choose.

Often times therapists think of genital surgeries and sexual function when contemplating work with transgender people. However, therapists have far more to offer transgender patients. For providing optimal care, knowledge of the intricacies of gender transition is essential. We provide that overview in this course. Topics covered include:

  • Societal influence on gender transition including interactions with health care providers
  • Recognizing difference between sex, sexuality, and gender
  • Understand the complexities of the legal system for the person transitioning gender
  • Tips and tools for a trauma-informed intake and examination
  • Health effects of hormones for gender transition as related to differential diagnosis in rehabilitation
  • Supporting healing after gender-affirming surgery
  • Operative procedures for face and chest
  • Operative procedures for masculinizing and feminizing genital surgery
  • Pre-operative evaluation, treatment, and education issues
  • Post-operative evaluation, treatment, education, and follow-up for genital surgeries
  • Outcome measures with rehab focus for people undergoing gender-affirming surgeries
  • Fertility and pregnancy in gender diverse people.
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The Importance of PNE

The Importance of PNE
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Alyson Lowrey, PT, DPT, OCS is the co-instructor for the H&W course Pain Science for the Chronic Pelvic Pain Population - Remote Course alongside Tara Sullivan, PT, DPT, PRPC, WCS, IF. Alyson treats the pelvic floor patient population through an orthopedic approach, working closely with pelvic floor specialists.

Pain neuroscience education (PNE) is the explanation of the neurophysiological changes in the central nervous system in patients with chronic pain. It includes how the nervous system functions and factors that influence its function such as social, psychological, and environmental factors. Pain neuroscience education aims to increase the patient’s knowledge about pain, decrease the threat of pain, and allow the patient to reconceptualize pain from a biopsychosocial perspective.

As a clinician seeing a patient with chronic and complex pain, it can be very daunting trying to determine how much education you should give the patient. Patients are generally very invested in improving their quality of life and therefore invested in learning how to treat their pain. Using techniques such as motivational interviewing is one way to determine if a patient is receptive to new information about pain and how to deliver that information. Education about pain needs to be varied and tailored to each patient based on their prior knowledge and perceptions, learning styles, their language, and their health literacy.

When a patient has an increased understanding of their pain and how their nervous system works, it can change their perspective about their pain by decreasing the threat value of their pain. PNE is the first step in the process of increasing a patient’s pain thresholds during exercise and functional activity. When patients no longer fear their pain as a sign of tissue damage, they can become empowered to re-educate their nervous system and pain processing centers in their brain. As providers, we are able to do this in several ways. We can do this by helping build new coping strategies and thought processes around their pain and dispelling misconceptions about their pain and physical ailments. We can suggest lifestyle and movement modifications that allow for more functional movement that doesn’t increase their pain activation centers. We can also adjust and modify our treatment plan around the patient's needs for success at each session. Consistently being a voice of encouragement, empowerment, and validation is also a very important component of PNE and our treatment as clinicians for our patients with chronic pain.


Pain Science for the Chronic Pelvic Pain Population - Remote Course

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Course Date
October 8th-9th

Description
This course provides a thorough introduction to pain science concepts including classifications of pain mechanisms, peripheral pain generators, peripheral sensitization and central sensitization in listed chronic pelvic pain conditions; as well as treatment strategies including therapeutic pain neuroscience education, therapeutic alliance, and the current rehab interventions' influence on central sensitization. The rehab professionals who attend will be provided the understanding and tools needed to identify and treat patients with chronic pelvic pain from a pain science perspective. Lecture topics include the history of pain, pain physiology, central and peripheral sensitization, sensitization in chronic pelvic pain conditions, therapeutic alliance, pain science and trauma-informed care, therapeutic pain neuroscience education, the influence of rehab interventions on the CNS, and specific case examples for sensitization in CPP.

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